Sinclair Method Studies
Published on: 11/06/2025
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
The Sinclair Method: The Benefits of Controlling Drinking with Naltrexone
Published on: 27/02/2025
Many people struggle with over drinking but feel resistant to total abstinence. The Sinclair Method (TSM) offers a science-based solution that helps individuals moderate their drinking naturally. Rather than relying on willpower alone, TSM uses Naltrexone, an opioid antagonist, to gradually reduce the brain’s reinforcement of alcohol consumption.
The Sinclair Method (TSM)
